{"id":16517,"date":"2026-02-24T16:30:16","date_gmt":"2026-02-24T15:30:16","guid":{"rendered":"https:\/\/preventionsida.org\/?page_id=16517"},"modified":"2026-02-24T16:52:44","modified_gmt":"2026-02-24T15:52:44","slug":"la-doxypep-une-nouvelle-strategie-de-prevention-des-ist-non-encore-recommandee-en-belgique","status":"publish","type":"page","link":"https:\/\/preventionsida.org\/fr\/protection\/la-doxypep-une-nouvelle-strategie-de-prevention-des-ist-non-encore-recommandee-en-belgique\/","title":{"rendered":"La DoxyPEP : une nouvelle strat\u00e9gie de pr\u00e9vention des IST ?"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":25,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-16517","page","type-page","status-publish","hentry"],"acf":{"sidebar":false,"contenu_flexible":[{"acf_fc_layout":"textfull","text":"<p class=\"western\" lang=\"fr-FR\" style=\"text-align: center;\" align=\"justify\"><span lang=\"fr-BE\" style=\"color: #fdb515;\"><b>\u00c0 l\u2019heure actuelle la DoxyPEP n\u2019est pas une strat\u00e9gie g\u00e9n\u00e9ralis\u00e9e de pr\u00e9vention recommand\u00e9e par le BREACH (Belgian Research on AIDS and HIV consortium). <\/b><\/span><\/p>\n<p><a class=\"western btn-center\" lang=\"fr-FR\" href=\"https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-Breach-statement-AL.pdf\" target=\"_blank\" rel=\"noopener\"><span lang=\"fr-BE\">D\u00e9couvrez ici l\u2019avis du BREACH<\/span><\/a><\/p>\n","background_color":true},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">de quoi s\u2019agit-il ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Depuis quelques ann\u00e9es, la pr\u00e9vention des <strong><a href=\"https:\/\/preventionsida.org\/fr\/ist\/les-ist-cest-quoi\/\">Infections Sexuellement Transmissibles (IST)<\/a><\/strong> conna\u00eet des \u00e9volutions majeures. Apr\u00e8s la <strong><a href=\"https:\/\/preventionsida.org\/fr\/protection\/la-prep\/\">PrEP<\/a><\/strong> contre le <strong><a href=\"https:\/\/preventionsida.org\/fr\/vih\/le-vih-cest-quoi\/\">VIH<\/a><\/strong>, une nouvelle approche fait parler d\u2019elle : la <\/span><span lang=\"fr-BE\"><b>DoxyPEP<\/b><\/span><span lang=\"fr-BE\">. Cette strat\u00e9gie, encore r\u00e9cente, suscite \u00e0 la fois beaucoup d\u2019espoir et des d\u00e9bats dans le monde m\u00e9dical.<\/span><\/p>\n<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Qu\u2019est-ce que la DoxyPEP ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">La <\/span><span lang=\"fr-BE\"><b>DoxyPEP<\/b><\/span><span lang=\"fr-BE\"> (<\/span>prophylaxie post exposition par doxycycline<span lang=\"fr-BE\">) consiste \u00e0 prendre un antibiotique, la <\/span><span lang=\"fr-BE\"><b>doxycycline<\/b><\/span><span lang=\"fr-BE\">, apr\u00e8s un rapport sexuel non prot\u00e9g\u00e9, afin de r\u00e9duire le risque de contracter certaines IST bact\u00e9riennes.<\/span><\/p>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Concr\u00e8tement il s\u2019agit de prendre en une prise, une dose de 200mg (2 comprim\u00e9s de 100mg ou 1 comprim\u00e9 de 200mg) dans un d\u00e9lai de 24-72h, apr\u00e8s le rapport \u00e0 risque.<\/span><\/p>\n<p lang=\"fr-FR\" align=\"justify\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-16565 size-large\" src=\"https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-1024x559.jpg\" alt=\"\" width=\"640\" height=\"349\" srcset=\"https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-1024x559.jpg 1024w, https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-300x164.jpg 300w, https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-768x419.jpg 768w, https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-1536x839.jpg 1536w, https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-2048x1118.jpg 2048w, https:\/\/preventionsida.org\/wp-content\/uploads\/2026\/02\/DoxyPEP-500x273.jpg 500w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Quelles IST sont concern\u00e9es ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les \u00e9tudes ont montr\u00e9 une efficacit\u00e9 significative de la DoxyPEP contre :<\/span><\/p>\n<ul>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\"><b>La <a href=\"https:\/\/preventionsida.org\/fr\/ist\/la-chlamydia\/\">chlamydia<\/a><\/b><\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\"><b>La <a href=\"https:\/\/preventionsida.org\/fr\/ist\/la-syphilis\/\">syphilis<\/a><\/b><\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">En revanche, son efficacit\u00e9 est <\/span><span lang=\"fr-BE\"><b>limit\u00e9e voire nulle contre la <a href=\"https:\/\/preventionsida.org\/fr\/ist\/la-gonorrhee\/\">gonorrh\u00e9e<\/a>.<\/b><\/span><\/p>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">La DoxyPEP <\/span><span lang=\"fr-BE\"><b>ne prot\u00e8ge pas contre le <a href=\"https:\/\/preventionsida.org\/fr\/vih\/le-vih-cest-quoi\/\">VIH<\/a><\/b><\/span><span lang=\"fr-BE\">, ni contre les IST virales comme l\u2019<strong><a href=\"https:\/\/preventionsida.org\/fr\/ist\/lherpes-genital\/\">herp\u00e8s<\/a><\/strong>, le <strong><a href=\"https:\/\/preventionsida.org\/fr\/ist\/lhpv\/\">HPV<\/a><\/strong> ou l\u2019<strong><a href=\"https:\/\/preventionsida.org\/fr\/ist\/les-hepatites-b-et-c\/\">h\u00e9patite C<\/a><\/strong>.<\/span><\/p>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Pour qui est-elle destin\u00e9e ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">\u00c0 l\u2019heure actuelle, la DoxyPEP est principalement \u00e9tudi\u00e9e et propos\u00e9e \u00e0 des <\/span><span lang=\"fr-BE\"><b>publics \u00e0 risque \u00e9lev\u00e9 d\u2019IST<\/b><\/span><span lang=\"fr-BE\">, notamment :<\/span><\/p>\n<ul>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les hommes ayant des relations sexuelles avec des hommes (HSH)<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les personnes trans*<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les personnes ayant d\u00e9j\u00e0 des IST r\u00e9p\u00e9t\u00e9es<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les personnes sous PrEP<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Elle n\u2019est <strong>pas recommand\u00e9e en autom\u00e9dication<\/strong> et doit s\u2019inscrire dans un <\/span><span lang=\"fr-BE\"><b>suivi m\u00e9dical r\u00e9gulier<\/b><\/span><span lang=\"fr-BE\">.<\/span><\/p>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Quels sont les b\u00e9n\u00e9fices observ\u00e9s ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Les essais cliniques men\u00e9s notamment aux \u00c9tats-Unis et en Europe ont montr\u00e9 :<\/span><\/p>\n<ul>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Une r\u00e9duction importante des infections \u00e0 <\/span><span lang=\"fr-BE\"><b><a href=\"https:\/\/preventionsida.org\/fr\/ist\/la-chlamydia\/\">chlamydia<\/a> et <a href=\"https:\/\/preventionsida.org\/fr\/ist\/la-syphilis\/\">syphilis<\/a><\/b><\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Une diminution du nombre total d\u2019IST chez les personnes utilisant la DoxyPEP<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Un outil compl\u00e9mentaire int\u00e9ressant aux strat\u00e9gies existantes (pr\u00e9servatif, d\u00e9pistage, PrEP)<\/span><\/p>\n<\/li>\n<\/ul>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Quels sont les risques et limites ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Malgr\u00e9 ses b\u00e9n\u00e9fices, la DoxyPEP soul\u00e8ve plusieurs pr\u00e9occupations dont les principales sont\u00a0:<\/span><\/p>\n<ul>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\"><b>Risque d\u2019antibior\u00e9sistance<\/b><\/span><span lang=\"fr-BE\"> : l\u2019utilisation r\u00e9p\u00e9t\u00e9e d\u2019antibiotiques pourrait favoriser l\u2019apparition de bact\u00e9ries r\u00e9sistantes.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\"><b>Faux sentiment de s\u00e9curit\u00e9<\/b><\/span><span lang=\"fr-BE\"> : elle ne remplace ni le <a href=\"https:\/\/preventionsida.org\/fr\/protection\/le-preservatif\/\"><strong>pr\u00e9servatif<\/strong><\/a> ni le <a href=\"https:\/\/preventionsida.org\/fr\/depistage\/le-depistage-des-ist\/\"><strong>d\u00e9pistage r\u00e9gulier<\/strong><\/a>.<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Pour ces raisons, de nombreux experts insistent sur une utilisation <\/span><span lang=\"fr-BE\"><b>cibl\u00e9e, encadr\u00e9e et temporaire<\/b><\/span><span lang=\"fr-BE\">.<\/span><\/p>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<h2 class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Quelle place dans la pr\u00e9vention aujourd\u2019hui ?<\/span><\/h2>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">La DoxyPEP n\u2019est pas une solution miracle, mais un <\/span><span lang=\"fr-BE\"><b>outil suppl\u00e9mentaire<\/b><\/span><span lang=\"fr-BE\"> dans la <strong><a href=\"https:\/\/preventionsida.org\/fr\/vih\/la-prevention-combinee-cest-quoi\/\">pr\u00e9vention combin\u00e9e<\/a><\/strong> des IST. Elle s\u2019int\u00e8gre dans une approche globale comprenant :<\/span><\/p>\n<ul>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Le <a href=\"https:\/\/preventionsida.org\/fr\/depistage\/le-depistage-des-ist\/\"><strong>d\u00e9pistage r\u00e9gulier<\/strong><\/a><\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">L\u2019information et la <a href=\"https:\/\/preventionsida.org\/fr\/protection\/se-proteger-lors-de-consommation-de-drogue\/\"><strong>r\u00e9duction des risques<\/strong><\/a><\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Le dialogue avec les professionnels de sant\u00e9<\/span><\/p>\n<\/li>\n<li>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">L\u2019utilisation du <a href=\"https:\/\/preventionsida.org\/fr\/protection\/le-preservatif\/\"><strong>pr\u00e9servatif<\/strong><\/a> quand c\u2019est possible<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"western\" lang=\"fr-FR\" align=\"justify\"><span lang=\"fr-BE\">Plusieurs pays commencent \u00e0 publier des recommandations officielles, tandis que d\u2019autres appellent \u00e0 la prudence en attendant davantage de donn\u00e9es \u00e0 long terme.<\/span><\/p>\n","background_color":false},{"acf_fc_layout":"textfull","text":"<blockquote>\n<h1 class=\"western\" lang=\"fr-FR\" style=\"text-align: center;\" align=\"justify\"><span lang=\"fr-BE\">La DoxyPEP repr\u00e9sente une <\/span><span lang=\"fr-BE\"><b>avanc\u00e9e prometteuse<\/b><\/span><span lang=\"fr-BE\"> dans la lutte contre certaines IST bact\u00e9riennes, mais sa g\u00e9n\u00e9ralisation reste encore probl\u00e9matique.<\/span><\/h1>\n<\/blockquote>\n","background_color":false}]},"_links":{"self":[{"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/pages\/16517","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/comments?post=16517"}],"version-history":[{"count":7,"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/pages\/16517\/revisions"}],"predecessor-version":[{"id":16571,"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/pages\/16517\/revisions\/16571"}],"up":[{"embeddable":true,"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/pages\/25"}],"wp:attachment":[{"href":"https:\/\/preventionsida.org\/fr\/wp-json\/wp\/v2\/media?parent=16517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}